Article
PRKCDBP (CAVIN3) and CRY2 associate with major depressive disorder.
Journal of affective disorders - 1 Jan 2017
Kovanen Leena, Donner Kati, Kaunisto Mari, Partonen Timo
Abstract excerpt
BACKGROUND: Dysfunctions in the intrinsic clocks are suggested in patients with depressive disorders. The cryptochrome circadian clocks 1 and 2 (CRY1 and CRY2) proteins modulate circadian rhythms in a cell and influence emotional reactions and mood in an individual. The protein kinase C delta binding protein (PRKCDBP, or CAVIN3), similar to the serum deprivation response protein (SDPR, or CAVIN2), reduces...
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