Article
CRY2 is associated with depression.
PloS one - 24 Feb 2010
Lavebratt Catharina, Sjöholm Louise K, Soronen Pia, Paunio Tiina, Vawter Marquis P, Bunney William E, Adolfsson Rolf, Forsell Yvonne, Wu Joseph C, Kelsoe John R, Partonen Timo, Schalling Martin
Abstract excerpt
BACKGROUND: Abnormalities in the circadian clockwork often characterize patients with major depressive and bipolar disorders. Circadian clock genes are targets of interest in these patients. CRY2 is a circadian gene that participates in regulation of the evening oscillator. This is of interest in mood disorders where a lack of switch from evening to morning oscillators has been postulated. PRINCIPAL FINDINGS: We...
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