High dietary saturated fat intake accentuates obesity risk associated with the fat mass and obesity-associated gene in adults.

doi:10.3945/jn.111.153460

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Article

High dietary saturated fat intake accentuates obesity risk associated with the fat mass and obesity-associated gene in adults.

The Journal of nutrition - 1 May 2012

Phillips Catherine M, Kesse-Guyot Emmanuelle, McManus Ross, Hercberg Serge, Lairon Denis, Planells Richard, Roche Helen M

Abstract excerpt

Fat mass and obesity-associated (FTO) is the strongest genetic determinant of obesity identified to date. Dietary fat is a key environmental factor that may interact with genotype to affect risk of obesity and metabolic syndrome (MetS). This study investigated associations among FTO rs9939609, obesity measures, and MetS phenotypes in adults and determined potential modulation by dietary fat intake at baseline and...

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PMID: 22457394
DOI: 10.3945/jn.111.153460

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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