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Article

Association study between a functional polymorphism of FK506-binding protein 51 (FKBP5) gene and personality traits in healthy subjects.

Neuroscience letters - 26 Nov 2010

Shibuya Naoshi, Suzuki Akihito, Sadahiro Ryoichi, Kamata Mitsuhiro, Matsumoto Yoshihiko, Goto Kaoru, Hozumi Yasukazu, Otani Koichi

Abstract excerpt

Previous studies have shown that the function of hypothalamic-pituitary-adrenal (HPA) axis is involved in the characterization of personality traits. FK506-binding protein 51 (FKBP51 or FKBP5) is a co-chaperone of heat-shock protein 90, and plays an important role in the negative feedback regulation of HPA axis function. It has been reported that a C/T single nucleotide polymorphism in the intron 2 of FKBP5 gene...

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Source

Identifiers

PMID: 20849924
DOI: 10.1016/j.neulet.2010.09.010

Genes

FKBP5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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