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Article

Association between FKBP5 Functional Polymorphisms and Completed Suicide.

Neuropsychobiology - 1 Jan 2015

Fudalej Sylwia, Kopera Maciej, Wołyńczyk-Gmaj Dorota, Fudalej Marcin, Krajewski Paweł, Wasilewska Krystyna, Szymański Konrad, Chojnicka Izabela, Podgórska Anna, Wojnar Marcin, Płoski Rafał

Abstract excerpt

OBJECTIVES: Dysfunction of the hypothalamic-pituitary-adrenal (HPA) axis leads to impaired stress response. FK506-binding protein 51 (FKBP5), which influences HPA axis activity via glucocorticoid receptors, is supposed to play an important role in the regulation of negative feedback and glucocorticoid resistance. Since ineffective stress response mechanisms are considered as a biological background of suicide...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26630184
DOI: 10.1159/000441659

Genes

FKBP5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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