[Direct cytopathic effects of particular hepatitis B virus genotypes in immunosuppressive condition].

doi:10.2222/jsv.60.79

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Article

[Direct cytopathic effects of particular hepatitis B virus genotypes in immunosuppressive condition].

Uirusu - 1 Jun 2010

Tanaka Yasuhito, Sugiyama Masaya, Mizokami Masashi

Abstract excerpt

Little is known about the direct cytopathic effect of hepatitis B virus (HBV) and its association with particular viral genotype or genetic mutation. In some immunosuppressed chronic HBV patients who had liver transplantation or HIV-coinfection, high viremia and liver fibrosis may occur. These findings suggest that hepatic injuries could arise in the absence of a mature immune system and the difference of...

Topics

Animals
Cells, Cultured
Genotype
Hepatitis B virus
Hepatocytes
Humans
Immune Tolerance
Liver Transplantation
Mice
Mutation
Virus Replication

Source

Open in PubMed

Identifiers

PMID: 20848867
DOI: 10.2222/jsv.60.79

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