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Article

Cellular apoptosis induced by replication of hepatitis B virus: possible link between viral genotype and clinical outcome.

Virology journal - 31 Oct 2007

Lu Yi Wei, Tan Tuan Lin, Zhang Jianhua, Chen Wei Ning

Abstract excerpt

HBV remains one of the major pathogens of liver diseases but the outcomes as inflammation, cirrhosis and cancer of the liver are greatly related to different viral genotypes. The aim of this study was to assess the pro-apoptotic effect of HBSP from three HBV genotypes on liver derived cells. HepG2 cells were applied in our system and transfected by HBV genotype A, B, and C. Cells were observed under phase...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17973991
DOI: 10.1186/1743-422X-4-117
PMCID: PMC2174443

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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