Article
Characterizing molecular adaptation: a hierarchical approach to assess the selective influence of amino acid properties.
Bioinformatics (Oxford, England) - 15 Nov 2010
Datta Saheli, Prado Raquel, Rodríguez Abel, Escalante Ananías A
Abstract excerpt
MOTIVATION: A number of methods for detecting positive selection in protein coding DNA sequences are based on whether each site/region has a non-synonymous to synonymous substitution rates ratio ω greater than one. However, a site/region may show a relatively large number of non-synonymous mutati...
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