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Article

Nuclear import mechanism for myocardin family members and their correlation with vascular smooth muscle cell phenotype.

The Journal of biological chemistry - 26 Nov 2010

Nakamura Seiji, Hayashi Ken'ichiro, Iwasaki Kazuhiro, Fujioka Tomoaki, Egusa Hiroshi, Yatani Hirofumi, Sobue Kenji

Abstract excerpt

Myocardin (Mycd), which is essential for the differentiation of the smooth muscle cell lineage, is constitutively located in the nucleus, although its family members, myocardin-related transcription factors A and B (MRTF-A/B), mostly reside in the cytoplasm and translocate to the nucleus in response to Rho signaling. The mechanism for their nuclear import is unclear. Here we investigated the mechanism for the...

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Identifiers

PMID: 20847050
DOI: 10.1074/jbc.M110.180786
PMCID: PMC2988337

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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