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Article

Evolutionary divergence and functions of the human acyl-CoA thioesterase gene ( ACOT ) family.

Human genomics - 1 Aug 2010

Brocker Chad, Carpenter Christopher, Nebert Daniel W, Vasiliou Vasilis

Abstract excerpt

The acyl-CoA thioesterase gene (ACOT ) family encodes enzymes that catalyse the hydrolysis of acyl-CoA thioester compounds, also known as activated fatty acids, to their corresponding non-esterified (free) fatty acid and coenzyme A (CoASH). These enzymes play a very important role in lipid metabolism by maintaining cellular levels and proper ratios of free and activated fatty acids, as well as CoASH. Within the...

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Identifiers

PMID: 20846931
DOI: 10.1186/1479-7364-4-6-411
PMCID: PMC3525216

Genes

THEM4
THEM5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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