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Article

Sterol esterification in yeast: a two-gene process.

Science (New York, N.Y.) - 31 May 1996

Yang H, Bard M, Bruner D A, Gleeson A, Deckelbaum R J, Aljinovic G, Pohl T M, Rothstein R, Sturley S L

Abstract excerpt

Unesterified sterol modulates the function of eukaryotic membranes. In human cells, sterol is esterified to a storage form by acyl-coenzyme A (CoA): cholesterol acyl transferase (ACAT). Here, two genes are identified, ARE1 and ARE2, that encode ACAT-related enzymes in yeast. The yeast enzymes are...

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Identifiers

PMID: 8650549
DOI: 10.1126/science.272.5266.1353

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-8650549-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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