Article
Evidence for 26 distinct acyl-coenzyme A synthetase genes in the human genome.
Journal of lipid research - 1 Dec 2007
Watkins Paul A, Maiguel Dony, Jia Zhenzhen, Pevsner Jonathan
Abstract excerpt
Acyl-coenzyme A synthetases (ACSs) catalyze the fundamental, initial reaction in fatty acid metabolism. "Activation" of fatty acids by thioesterification to CoA allows their participation in both anabolic and catabolic pathways. The availability of the sequenced human genome has facilitated the investigation of the number of ACS genes present. Using two conserved amino acid sequence motifs to probe human DNA...
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