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Article

Actinohivin: specific amino acid residues essential for anti-HIV activity.

The Journal of antibiotics - 1 Nov 2010

Takahashi Atsushi, Inokoshi Junji, Tsunoda Masaru, Suzuki Kaoru, Takenaka Akio, Sekiguchi Takeshi, Omura Satoshi, Tanaka Haruo

Abstract excerpt

Actinohivin (AH) is a microbial lectin containing 114 amino acids, which inhibits human immunodeficiency virus (HIV) infection. This effect is brought about by its specific binding to Man-α(1-2)-Man unit(s) of high-mannose type glycan (HMTG) bound to HIV gp120. The recently determined crystal str...

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Identifiers

PMID: 20842142
DOI: 10.1038/ja.2010.106

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20842142-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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