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Article

Catecholamine-o-methyltransferase polymorphisms are associated with postoperative pain intensity.

The Clinical journal of pain - 1 Feb 2011

Lee Peter J, Delaney Patrick, Keogh John, Sleeman Duncan, Shorten George D

Abstract excerpt

OBJECTIVES: single nucleotide polymorphisms (SNPs) in the genes for catecholamine-O-methyltransferase (COMT), μ-opioid receptor and GTP cyclohydrolase (GCH1) have been linked to acute and chronic pain states. COMT polymorphisms are associated with experimental pain sensitivity and a chronic pain...

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Source

Identifiers

PMID: 20842020
DOI: 10.1097/AJP.0b013e3181f15885

Genes

COMT
GCH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20842020-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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