Article
Natural variation in the μ-opioid gene OPRM1 predicts increased pain on third day after thoracotomy.
The Clinical journal of pain - 1 Jan 2000
Ochroch Edward Andrew, Vachani Anil, Gottschalk Allan, Kanetsky Peter A
Abstract excerpt
OBJECTIVES: The mechanism whereby acute postsurgical pain can persist and become chronic remains unknown. Thoracotomy is a common procedure with a high incidence of long-term pain for which acute postsurgical pain is an established risk factor. Therefore, the genetic basis of elevations in acute postsurgical pain after thoracotomy was investigated. METHODS: A cohort of thoracotomy patients participating in an...
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