Heterozygosity effects in studies of genetic markers and disease.

doi:10.1159/000153955

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Article

Heterozygosity effects in studies of genetic markers and disease.

Human heredity - 1 Jan 1990

Beckman L, Fröhlander N

Abstract excerpt

Examples were discussed where heterozygosity was associated with increased or decreased disease risks and where the apparent mechanism is direct functional involvement of gene products and not linkage disequilibrium. Special attention was paid to the impact of Hp (haptoglobin) heterozygosity on a...

Topics

Arthritis, Rheumatoid
Genetic Markers
Haptoglobins
Heterozygote
Humans
Phenotype
Psoriasis
Risk
Uremia

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