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New frontiers in circulating tumor cell analysis: A reference guide for biomolecular profiling toward translational clinical use

12 Oct 2013

Abstract excerpt

Circulating tumor cells (CTCs) are now routinely isolated from blood, and measurement of CTC concentrations appears to correlate well with survival in patients with cancer. Interrogation of the molecular profile of CTCs for expression of protein biomarkers, genetic variants and gene expression provides opportunities to use this information to guide personalized treatment, monitor therapy and detect emerging...

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PMID: 24122526
DOI: 10.1002/ijc.28516

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