Article
Chromosome 9p21 variant predicts mortality after coronary artery bypass graft surgery.
Circulation - 14 Sept 2010
Muehlschlegel Jochen D, Liu Kuang-Yu, Perry Tjörvi E, Fox Amanda A, Collard Charles D, Shernan Stanton K, Body Simon C
Abstract excerpt
BACKGROUND: Recent genome-wide association studies have identified several chromosome 9p21 single nucleotide polymorphisms associated with coronary artery disease and myocardial infarction in nonsurgical populations. We have recently demonstrated an independent association between these 9p21 variants and perioperative myocardial injury after isolated primary coronary artery bypass graft (CABG) surgery. This study...
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