Article
Reduced risk of recurrent myocardial infarction in homozygous carriers of the chromosome 9p21 rs1333049 C risk allele in the contemporary percutaneous coronary intervention era: a prospective observational study.
BMJ open - 1 Jan 2014
Hara Masahiko, Sakata Yasuhiko, Nakatani Daisaku, Suna Shinichiro, Usami Masaya, Matsumoto Sen, Ozaki Kouichi, Nishino Masami, Sato Hiroshi, Kitamura Tetsuhisa, Nanto Shinsuke, Hamasaki Toshimitsu, Tanaka Toshihiro, Hori Masatsugu, Komuro Issei
Abstract excerpt
OBJECTIVES: Chromosome 9p21 single nucleotide polymorphism (SNP) is a susceptibility variant for acute myocardial infarction (AMI) in the primary prevention setting. However, it is controversial whether this SNP is also associated with recurrent myocardial infarction (ReMI) in the secondary prevention setting. The purpose of this study is to evaluate the impact of chromosome 9p21 SNP on ReMI in patients receiving...
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