Article
Antimicrobial susceptibility pattern and sequence analysis of DNA gyrase and DNA topoisomerase IV in Salmonella enterica serovars Typhi and Paratyphi A isolates with decreased susceptibility to ciprofloxacin.
Transactions of the Royal Society of Tropical Medicine and Hygiene - 1 Aug 2016
Misra Richa, Thakare Ritesh, Amrin N, Prasad Kashi Nath, Chopra Sidharth, Dhole Tapan Nirodhechand
Abstract excerpt
BACKGROUND: We describe the antimicrobial susceptibility pattern of 100 typhoidal Salmonella isolates recovered from blood cultures and also investigate the association of decreased ciprofloxacin susceptibility with mutations in the genes coding for DNA gyrase and topoisomerase IV in 55 isolates. METHODS: The study was conducted between January 2013 and December 2015 at a tertiary care centre in north India....
Topics
- Anti-Bacterial Agents
- Bacterial Proteins
- Ciprofloxacin
- DNA Gyrase
- DNA Topoisomerase IV
- Disk Diffusion Antimicrobial Tests
- Drug Resistance, Bacterial
- Fluoroquinolones
- Genotype
- Humans
- India
- Microbial Sensitivity Tests