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Article

Early impairment of transmural principal strains in the left ventricular wall after short-term, high-fat feeding of mice predisposed to cardiac steatosis.

Circulation. Cardiovascular imaging - 1 Nov 2010

Hankiewicz Janusz H, Banke Natasha H, Farjah Mariam, Lewandowski E Douglas

Abstract excerpt

BACKGROUND: myocardial lipid accumulation precedes some cardiomyopathies, but little is known of concurrent effects on ventricular mechanics. We tested the hypothesis that intramyocardial lipid accumulation during a short-term, high-fat diet (HFD) affects 2-dimensional strains in the heart. We examined the hearts of nontransgenic (NTG) mice and of transgenic mice predisposed to elevated triacylglyceride (TAG)...

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Identifiers

PMID: 20837747
DOI: 10.1161/CIRCIMAGING.110.959098
PMCID: PMC3072284

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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