Article
Association of Central Adiposity With Adverse Cardiac Mechanics: Findings From the Hypertension Genetic Epidemiology Network Study.
Circulation. Cardiovascular imaging - 1 Jun 2016
Selvaraj Senthil, Martinez Eva E, Aguilar Frank G, Kim Kwang-Youn A, Peng Jie, Sha Jin, Irvin Marguerite R, Lewis Cora E, Hunt Steven C, Arnett Donna K, Shah Sanjiv J
Abstract excerpt
BACKGROUND: Central obesity, defined by increased waist circumference or waist:hip ratio (WHR), is associated with increased cardiovascular events, including heart failure. However, the pathophysiological link between central obesity and adverse cardiovascular outcomes remains poorly understood. We hypothesized that central obesity and larger WHR are independently associated with worse cardiac mechanics (reduced...
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