Article
Effect of clinical factors and gene polymorphism of CYP2C19*2, *17 and CYP4F2*3 on early stent thrombosis.
Pharmacogenomics - 1 Jan 2015
Kupstyte Nora, Zaliunas Remigijus, Tatarunas Vacis, Skipskis Vilius, Zaliaduonyte-Peksiene Diana, Grabauskyte Ingrida, Dovidaitiene Dovile, Bumblauskas Karolis, Gustiene Olivija, Lesauskaite Vaiva
Abstract excerpt
AIM: To determine the main clinical and genetic factors having impact on early coronary stent thrombosis. MATERIALS & METHODS: Genotyping of CYP2C19*2, *17 and CYP4F2*3 in patients with (n = 31) and without stent thrombosis (n = 456) was performed. Clinical and genetic data were analyzed by binary logistic regression. RESULTS: Smoking (OR: 0.317; 95% CI: 0.131-0.767), high-density lipoprotein level in mmol/l (OR:...
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