Article
Tau and 14-3-3 of genetic and sporadic Creutzfeldt-Jakob disease patients in Israel.
Journal of neurology - 1 Feb 2011
Meiner Zeev, Kahana Esther, Baitcher Fanny, Korczyn Amos D, Chapman Joab, Cohen Oren S, Milo Ron, Aharon-Perez Judith, Abramsky Oded, Gabizon Ruth, Rosenmann Hanna
Abstract excerpt
One of the largest clusters of genetic Creutzfeldt-Jakob disease (gCJD) is found among Jews of Libyan origin in Israel and is linked to the E200K mutation in PRNP (gCJDE200K). The aim of this study was to compare the levels of cerebrospinal fluid (CSF) biomarkers, Tau and 14-3-3 proteins, between gCJDE200K patients, sporadic CJD (sCJD) patients and non-CJD controls in Israel between the years 1996-2006. The...
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