Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transcriptional Reprogramming in Nonhuman Primate (Rhesus Macaque) Tuberculosis Granulomas

31 Aug 2010

Abstract excerpt

BACKGROUND: In response to Mtb infection, the host remodels the infection foci into a dense mass of cells known as the granuloma. The key objective of the granuloma is to contain the spread of Mtb into uninfected regions of the lung. However, it appears that Mtb has evolved mechanisms to resist killing in the granuloma. Profiling granuloma transcriptome will identify key immune signaling pathways active during TB...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diagnosis and treatment of tuberculosis
Share to Infectious Diseases and Tuberculosis
Share to Tuberculosis Research and Epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20824205
DOI: 10.1371/journal.pone.0012266

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transcriptional Reprogramming in Nonhuman Primate (Rhesus Macaque) Tuberculosis GranulomasPMID 20824205Read ↗

Spatial transcriptomic analysis of HIV and tuberculosis coinfection in a humanized mouse model reveals unique transcription patterns, immune responses and early morphological alterationsSemantic proximity Read ↗

Hypoxia Sensing and Persistence Genes Are Expressed during the Intragranulomatous Survival of Mycobacterium tuberculosisSemantic proximity Read ↗

Spatial Organization and Recruitment of Non-Specific T Cells May Limit T Cell-Macrophage Interactions Within Mycobacterium tuberculosis GranulomasSemantic proximity Read ↗

Single-cell transcriptomic profiling reveals a novel signature of necrotizing granulomatous lesions in the lungs of <i>Mycobacterium tuberculosis</i> -infected C3HeB/FeJ miceSemantic proximity Read ↗

Understanding the development of tuberculous granulomas: insights into host protection and pathogenesis, a review in humans and animalsSemantic proximity Read ↗

A multicenter spatial transcriptomics atlas of human tuberculosis and non-tuberculous mycobacterial diseaseSemantic proximity Read ↗

Airway immune signatures of protection and disease progression in recent human tuberculosis household contactsSemantic proximity Read ↗

Airway immune signatures of protection and disease progression in recent human tuberculosis household contactsSemantic proximity Read ↗

Unravelling the transcriptome of the human tuberculosis lesion and its clinical implicationsSemantic proximity Read ↗

Transcriptomic Insights into Mycobacterium orygis Infection-associated Pulmonary Granulomas Reveal Multicellular Immune Networks and Tuberculosis Biomarkers in Cattle.Semantic proximity Read ↗

Deletion of TGF-β1 Increases Bacterial Clearance by Cytotoxic T Cells in a Tuberculosis Granuloma ModelSemantic proximity Read ↗

Species-specific iNOS expression distinguishes epithelial and myeloid IFNγ responses in tuberculosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.