Article
Candidate gene prioritization based on spatially mapped gene expression: an application to XLMR.
Bioinformatics (Oxford, England) - 15 Sept 2010
Piro Rosario M, Molineris Ivan, Ala Ugo, Provero Paolo, Di Cunto Ferdinando
Abstract excerpt
MOTIVATION: The identification of genes involved in specific phenotypes, such as human hereditary diseases, often requires the time-consuming and expensive examination of a large number of positional candidates selected by genome-wide techniques such as linkage analysis and association studies. Even considering the positive impact of next-generation sequencing technologies, the prioritization of these positional...
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