Article
Prioritization of positional candidate genes using multiple web-based software tools.
Twin research and human genetics : the official journal of the International Society for Twin Studies - 1 Dec 2007
Thornblad Tobias A, Elliott Kate S, Jowett Jeremy, Visscher Peter M
Abstract excerpt
The prioritization of genes within a candidate genomic region is an important step in the identification of causal gene variants affecting complex traits. Surprisingly, there have been very few reports of bioinformatics tools to perform such prioritization. The purpose of this article is to investigate the performance of 3 positional candidate gene software tools available, PosMed, GeneSniffer and SUSPECTS. The...
Topics
- Breast Neoplasms
- Crohn Disease
- Female
- Genes, BRCA1
- Genetic Predisposition to Disease
- Genome, Human
- Genomics
- Humans
- Internet
- Macular Degeneration
- Male