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Article

MicroRNA-related genetic variations as predictors for risk of second primary tumor and/or recurrence in patients with early-stage head and neck cancer.

Carcinogenesis - 1 Dec 2010

Zhang Xiaofan, Yang Hushan, Lee J Jack, Kim Edward, Lippman Scott M, Khuri Fadlo R, Spitz Margaret R, Lotan Reuben, Hong Waun K, Wu Xifeng

Abstract excerpt

Second primary tumor (SPT) and/or recurrence negatively impact the prognosis of patients with curatively treated early-stage head and neck cancer. MicroRNAs (miRNAs) play important roles in cancer development. We explored whether the variations of miRNA-related pathway were associated with the risk of SPT/recurrence in patients with early-stage head and neck cancer. This study includes 150 early-stage head and...

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Identifiers

PMID: 20819778
DOI: 10.1093/carcin/bgq177
PMCID: PMC3105587

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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