Article
Human periosteum-derived cells maintain phenotypic stability and chondrogenic potential throughout expansion regardless of donor age.
Arthritis and rheumatism - 1 Jan 2001
De Bari C, Dell'Accio F, Luyten F P
Abstract excerpt
OBJECTIVE: To assess the in vitro chondrogenic potential of adult human periosteum-derived cells (PDCs) with regard to the number of cell passages and the age of the donor. METHODS: Cells were enzymatically released from the periosteum of the proximal tibia obtained from adult human donors and expanded in monolayer. PDCs were harvested at multiple passages for total RNA extraction and semiquantitative reverse...
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