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Article

Tailspike interactions with lipopolysaccharide effect DNA ejection from phage P22 particles in vitro.

The Journal of biological chemistry - 19 Nov 2010

Andres Dorothee, Hanke Christin, Baxa Ulrich, Seul Anaït, Barbirz Stefanie, Seckler Robert

Abstract excerpt

Initial attachment of bacteriophage P22 to the Salmonella host cell is known to be mediated by interactions between lipopolysaccharide (LPS) and the phage tailspike proteins (TSP), but the events that subsequently lead to DNA injection into the bacterium are unknown. We used the binding of a fluorescent dye and DNA accessibility to DNase and restriction enzymes to analyze DNA ejection from phage particles in...

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Identifiers

PMID: 20817910
DOI: 10.1074/jbc.M110.169003
PMCID: PMC2978605

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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