Article
Interaction of Salmonella phage P22 with its O-antigen receptor studied by X-ray crystallography.
Biological chemistry - 1 Jan 2000
Steinbacher S, Miller S, Baxa U, Weintraub A, Seckler R
Abstract excerpt
The O-antigenic repeating units of the Salmonella cell surface lipopolysaccharides (serotypes A, B and D1) serve as receptors for phage P22. This initial binding step is mediated by the tailspike protein (TSP), which is present in six copies on the base plate of the phage. In addition to the binding activity, TSP also displays a low endoglycolytic activity, cleaving the alpha(1,3)-O-glycosidic bond between...
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