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Article

Effects of CYP2C93 and CYP2C913 on Diclofenac Metabolism and Inhibition-based Drug-Drug Interactions.

Drug metabolism and pharmacokinetics - 1 Jan 2010

Zi Jing, Liu Duan, Ma Pingping, Huang He, Zhu Juanli, Wei Dongqing, Yang Jin, Chen Chao

Abstract excerpt

Cytochrome P450 2C9 (CYP2C9) is a polymorphic enzyme responsible for the metabolism of many important drugs, including diclofenac. CYP2C9*3 and CYP2C9*13 are the principal variant alleles found in the Chinese population. CYP2C9*3 has been reported to reduce the metabolism of diclofenac and alter...

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Source

Identifiers

PMID: 20814155
DOI: 10.2133/dmpk.dmpk-10-rg-009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20814155-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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