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Article

Conditions under which genome-wide association studies will be positively misleading.

Genetics - 1 Nov 2010

Platt Alexander, Vilhjálmsson Bjarni J, Nordborg Magnus

Abstract excerpt

Genome-wide association mapping is a popular method for using natural variation within a species to generate a genotype-phenotype map. Statistical association between an allele at a locus and the trait in question is used as evidence that variation at the locus is responsible for variation of the trait. Indirect association, however, can give rise to statistically significant results at loci unrelated to the...

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PMID: 20813880
DOI: 10.1534/genetics.110.121665
PMCID: PMC2975277

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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