Article
Fine mapping by composite genome-wide association analysis.
Genetics research - 6 Jun 2017
Casellas Joaquim, Cañas-Álvarez Jhon Jacobo, Fina Marta, Piedrafita Jesús, Cecchinato Alessio
Abstract excerpt
Genome-wide association (GWA) studies play a key role in current genetics research, unravelling genomic regions linked to phenotypic traits of interest in multiple species. Nevertheless, the extent of linkage disequilibrium (LD) may provide confounding results when significant genetic markers span along several contiguous cM. In this study, we have adapted the composite interval mapping approach to the GWA...
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