Article
The complete linkage disequilibrium test: a test that points to causative mutations underlying quantitative traits.
Genetics, selection, evolution : GSE - 23 May 2011
Uleberg Eivind, Meuwissen Theo He
Abstract excerpt
BACKGROUND: Genetically, SNP that are in complete linkage disequilibrium with the causative SNP cannot be distinguished from the causative SNP. The Complete Linkage Disequilibrium (CLD) test presented here tests whether a SNP is in complete LD with the causative mutation or not. The performance of the CLD test is evaluated in 1000 simulated datasets. METHODS: The CLD test consists of two steps i.e. analysis I and...
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