Article
Molecular genetic studies of complex phenotypes.
Translational research : the journal of laboratory and clinical medicine - 1 Feb 2012
Marian Ali J
Abstract excerpt
The approach to molecular genetic studies of complex phenotypes evolved considerably during the recent years. The candidate gene approach, which is restricted to an analysis of a few single-nucleotide polymorphisms (SNPs) in a modest number of cases and controls, has been supplanted by the unbiased approach of genome-wide association studies (GWAS), wherein a large number of tagger SNPs are typed in many...
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