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Article

Aberrant expression of CD6 on B-cell subsets from patients with Sjögren’s syndrome

1 Sept 2010

Abstract excerpt

CD6 is one of a pair of related genes encoding CD5-associated receptors on all T cells and a subset of B cells. The current availability of "T1h", a humanized anti-CD6 monoclonal antibody for B cell-mediated autoimmune disorders revives analysis of the B-cell subset expression of CD6, particularly in primary Sjögren's syndrome (SS). Refined phenotype of B-lymphocytes peripheral blood (PB), bone marrow and tonsils...

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Identifiers

PMID: 20810246
DOI: 10.1016/j.jaut.2010.07.005

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