Article
ALOX5AP and LTA4H polymorphisms modify augmentation of bronchodilator responsiveness by leukotriene modifiers in Latinos.
The Journal of allergy and clinical immunology - 1 Oct 2010
Tcheurekdjian Haig, Via Marc, De Giacomo Anthony, Corvol Harriet, Eng Celeste, Thyne Shannon, Chapela Rocio, Rodriguez-Cintron William, Rodriguez-Santana Jose R, Avila Pedro C, Burchard Esteban González
Abstract excerpt
BACKGROUND: Understanding the effects of interactions between multiple genes and asthma medications may aid in the understanding of the heterogeneous response to asthma therapies. OBJECTIVE: To identify modulating effects of arachidonate 5-lipoxygenase-activating protein (ALOX5AP) and leukotriene A(4) hydrolase (LTA4H) gene polymorphisms on the drug-drug interaction between leukotriene modifiers and albuterol in...
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