Article
Aptamer-functionalized in situ injectable hydrogel for controlled protein release.
Biomacromolecules - 11 Oct 2010
Soontornworajit Boonchoy, Zhou Jing, Zhang Zhaoyang, Wang Yong
Abstract excerpt
Various in situ injectable hydrogels have been developed for protein delivery in treating human diseases. However, most hydrogels are highly permeable, which can lead to the rapid release of loaded proteins. The purpose of this study is to apply nucleic acid aptamers to functionalize an in situ injectable hydrogel model to control the release of proteins. The aptamers were studied using secondary structural...
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