Article
Avidity-controlled delivery of angiogenic peptides from injectable molecular-recognition hydrogels.
Tissue engineering. Part A - 1 Aug 2014
Mulyasasmita Widya, Cai Lei, Hori Yuki, Heilshorn Sarah C
Abstract excerpt
Peptide mimics of growth factors represent an emerging class of therapeutic drugs due to high biological specificity and relative ease of synthesis. However, maintaining efficacious therapeutic dosage at the therapy site has proven challenging owing to poor intestinal permeability and short circulating half-lives in the blood stream. In this work, we present the affinity immobilization and controlled release of...
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