Article
Absence of the 7-repeat variant of the DRD4 VNTR is associated with drifting sustained attention in children with ADHD but not in controls.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Sept 2008
Johnson Katherine A, Kelly Simon P, Robertson Ian H, Barry Edwina, Mulligan Aisling, Daly Michael, Lambert David, McDonnell Caroline, Connor Thomas J, Hawi Ziarih, Gill Michael, Bellgrove Mark A
Abstract excerpt
Many genetic studies have demonstrated an association between the 7-repeat (7r) allele of a 48-base pair variable number of tandem repeats (VNTR) in exon 3 of the DRD4 gene and the phenotype of attention deficit hyperactivity disorder (ADHD). Previous studies have shown inconsistent associations between the 7r allele and neurocognitive performance in children with ADHD. We investigated the performance of 128...
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