Article
Co-regulation of alternative splicing by diverse splicing factors in Caenorhabditis elegans.
Nucleic acids research - 1 Jan 2011
Barberan-Soler Sergio, Medina Pedro, Estella Jeffrey, Williams James, Zahler Alan M
Abstract excerpt
Regulation of alternative splicing is controlled by pre-mRNA sequences (cis-elements) and trans-acting protein factors that bind them. The combinatorial interactions of multiple protein factors with the cis-elements surrounding a given alternative splicing event lead to an integrated splicing decision. The mechanism of multifactorial splicing regulation is poorly understood. Using a splicing-sensitive DNA...
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