Article
Transgenic alternative-splicing reporters reveal tissue-specific expression profiles and regulation mechanisms in vivo.
Nature methods - 1 Nov 2006
Kuroyanagi Hidehito, Kobayashi Tetsuo, Mitani Shohei, Hagiwara Masatoshi
Abstract excerpt
Alternative splicing of pre-mRNAs allows multicellular organisms to create a huge diversity of proteomes from a finite number of genes. But extensive studies in vitro or in cultured cells have not fully explained the regulation mechanisms of tissue-specific or developmentally regulated alternativ...
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