Article
Characterization of cDNA and genomic clones encoding human myelin oligodendrocyte glycoprotein.
Journal of neurochemistry - 1 Jul 1995
Hilton A A, Slavin A J, Hilton D J, Bernard C C
Abstract excerpt
Myelin oligodendrocyte glycoprotein (MOG) is a transmembrane protein expressed only in the CNS and is a possible target autoantigen in multiple sclerosis (MS). To further study the association of MOG with MS, we have characterized cDNA and genomic clones encoding human MOG. The human MOG cDNA, li...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Blotting, Northern
- Cloning, Molecular
- DNA, Complementary
- Genetic Variation
- Genome, Human
- Humans
- Membrane Glycoproteins
- Molecular Sequence Data
- Myelin Proteins
- Myelin-Associated Glycoprotein
- Myelin-Oligodendrocyte Glycoprotein
- Oligodendroglia
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- RNA, Messenger