Article
Serotonin transporter polymorphism as a predictor for escitalopram treatment of major depressive disorder comorbid with alcohol dependence.
Psychiatry research - 30 Mar 2011
Muhonen Leea H, Lahti Jari, Alho Hannu, Lönnqvist Jouko, Haukka Jari, Saarikoski Sirkku T
Abstract excerpt
The aim of this study was to determine whether the serotonin transporter gene polymorphism (5-HTTLPR) is associated with the treatment outcomes of escitalopram for patients with comorbid major depression and alcohol dependence. Eighty treatment-seeking patients were randomly assigned to either receive 20mg of escitalopram or a control of 20mg of the non-serotonergically acting memantine. Depression was measured...
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