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Atomic model of vesicular stomatitis virus and mechanism of assembly

10 Oct 2022

Abstract excerpt

Like other negative-strand RNA viruses (NSVs) such as influenza and rabies, vesicular stomatitis virus (VSV) has a three-layered organization: a layer of matrix protein (M) resides between the glycoprotein (G)-studded membrane envelope and the nucleocapsid, which is composed of the nucleocapsid protein (N) and the encapsidated genomic RNA. Lack of in situ atomic structures of these viral components has limited...

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PMID: 36216930
DOI: 10.1038/s41467-022-33664-4

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