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Hepatocyte organoids and cell transplantation: What the future holds

1 Oct 2021

Abstract excerpt

Historically, primary hepatocytes have been difficult to expand or maintain in vitro. In this review, we will focus on recent advances in establishing hepatocyte organoids and their potential applications in regenerative medicine. First, we provide a background on the renewal of hepatocytes in the homeostatic as well as the injured liver. Next, we describe strategies for establishing primary hepatocyte organoids...

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PMID: 34663941
DOI: 10.1038/s12276-021-00579-x

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