Article
Transgene‐mediated suppression of dengue viruses in the salivary glands of the yellow fever mosquito, Aedes aegypti
6 Aug 2010
Abstract excerpt
Controlled sex-, stage- and tissue-specific expression of antipathogen effector molecules is important for genetic engineering strategies to control mosquito-borne diseases. Adult female salivary glands are involved in pathogen transmission to human hosts and are target sites for expression of antipathogen effector molecules. The Aedes aegypti 30K a and 30K b genes are expressed exclusively in adult female...
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