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Article

Dengue subgenomic flaviviral RNA disrupts immunity in mosquito salivary glands to increase virus transmission

28 Jul 2017

Abstract excerpt

Globally re-emerging dengue viruses are transmitted from human-to-human by Aedes mosquitoes. While viral determinants of human pathogenicity have been defined, there is a lack of knowledge of how dengue viruses influence mosquito transmission. Identification of viral determinants of transmission can help identify isolates with high epidemiological potential. Additionally, mechanistic understanding of transmission...

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PMID: 28753642
DOI: 10.1371/journal.ppat.1006535

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