Article
Relating the liver damage with hepatitis C virus polymorphism in core region and human variables in HIV-1-coinfected patients.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Dec 2010
Matas Marina, Picornell Antònia, Cifuentes Carmen, Payeras Antoni, Bassa Antoni, Homar Francesc, López-Labrador F Xavier, Moya Andrés, Ramon Maria M, Castro José A
Abstract excerpt
Hepatitis C virus (HCV) infection is the most important cause of chronic hepatitis, cirrhosis and end-stage liver disease leading to liver transplantation worldwide. Chronic infection by HCV causes liver fibrosis, which is accelerated by unknown mechanisms in patients with human immunodeficiency virus-1 (HIV-1) coinfection. Although the genetic variability of both HCV and HIV has been extensively studied in the...
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